HMG 75iu

Key Chemical Details:

• CAS Number: 61489-71-2

• Molecular Formula: Variable/complex (glycoprotein mixture; often simplified in databases as C₉H₁₈O due to catalog placeholders, but actual structure is large heterodimeric glycoproteins)

• Molecular Weight: Variable; approximately 25,000–40,000 Da per hormone dimer (FSH ~30–35 kDa, LH ~28–30 kDa, depending on glycosylation); some vendor listings use 142.24 g/mol (from simplified database entry, not reflective of the full complex)

• Composition:

  • Heterodimeric glycoproteins: Common α-subunit (~92 amino acids) + specific β-subunits (FSH β: ~111 amino acids; LH β: ~121 amino acids)

  • Extensively glycosylated (N- and O-linked carbohydrates contribute to molecular weight, stability, and bioactivity)

  • No single linear amino acid sequence (unlike small peptides); bioactivity measured in International Units (IU)

• PubChem CID: 21888462 (for Menotropins/Human Menopausal Gonadotrophin entry)

• Appearance (typical research grade): White to off-white lyophilized powder

• Storage: Typically -20°C (as lyophilized powder for stability); reconstituted: 2–8°C refrigerated or frozen aliquots

• Other Properties:

  • Biological activity: 75 IU FSH + 75 IU LH per vial (1:1 ratio, standardized by bioassay)

  • Amphiphilic and highly polar due to glycosylation and amino acid composition

  • pH of reconstituted solution: Neutral to slightly acidic

  • Sensitive to heat, light, and improper handling

Disclaimers:

• Strictly for qualified laboratory research use by professionals.

• Not FDA-approved; no therapeutic, diagnostic, or human/veterinary applications.

• Purity typically ≥98–99% (HPLC/potency assays); batch-specific third-party Certificates of Analysis (COAs) confirm identity, potency, and contaminants.

• Handle according to standard lab safety protocols.