NAD+ 500mg

NAD⁺ (Nicotinamide Adenine Dinucleotide, oxidized form)

Intended for laboratory research purposes only. Not for human consumption

NAD⁺ is an essential coenzyme found in all living cells, serving as a cofactor in redox reactions, energy metabolism (e.g., glycolysis, TCA cycle, oxidative phosphorylation), DNA repair, sirtuin activation, and poly(ADP-ribose) polymerase (PARP) signaling.

Key Chemical Details:

• CAS Number: 53-84-9

• Molecular Formula: C₂₁H₂₇N₇O₁₄P₂ (oxidized form; often listed as C₂₁H₂₈N₇O₁₄P₂⁺ for the protonated cation)

• Molecular Weight: 663.4–664.4 g/mol (commonly listed as 663.43 or 664.4; exact monoisotopic mass ≈663.12 Da)

• Structure: Dinucleotide consisting of nicotinamide riboside linked by pyrophosphate to adenosine monophosphate (no linear amino acid sequence; it’s a nucleotide coenzyme, not a peptide)

• PubChem CID: 5893 (primary for Nadide/NAD⁺; related entries include 925 for beta-NAD, 10897651 for variants)

• Appearance (typical research grade): White to off-white lyophilized powder

• Solubility: Readily soluble in water (high solubility in aqueous buffers); typically reconstitutes easily for lab use

• Storage: Typically -20°C (as lyophilized powder for stability); protect from light, moisture, and repeated freeze-thaw cycles (NAD⁺ is sensitive to hydrolysis and degradation)

• Other Properties:

  • Redox-active (NAD⁺/NADH pair; oxidized form accepts electrons)

  • Highly polar and charged (multiple phosphate groups, nitrogenous bases)

  • pH-sensitive; stable in neutral to slightly acidic conditions but degrades in alkaline environments

  • Contains ribose sugars, adenine, nicotinamide, and pyrophosphate linkages

Disclaimers:

• Strictly for qualified laboratory research professionals.

• Not FDA-approved; no therapeutic, diagnostic, or human-use applications

• Purity typically ≥98–99% (HPLC); batch-specific third-party Certificates of Analysis (COAs) available for identity, purity, and contaminants.

• Handle according to standard lab safety protocols.